The original paper is in English. Non-English content has been machine-translated and may contain typographical errors or mistranslations. ex. Some numerals are expressed as "XNUMX".
Copyrights notice
The original paper is in English. Non-English content has been machine-translated and may contain typographical errors or mistranslations. Copyrights notice
의료용 마이크로니들(MN)에는 주사기 등 약물 투여 도구를 내장하는 것이 필요하다. 이를 통해 의료인이 아닌 사람도 약물 투여를 더 쉽게 할 수 있습니다. 속이 빈 MN을 제작하는 것이 어렵기 때문에 MN과 그 기판에 모세관 홈을 제작하여 더 많은 용량을 투여할 수 있도록 했습니다. MN 그루빙은 폴리락트산에 사용되는 기존의 사출성형 방식으로는 구현하기 어렵습니다. 따라서 생분해성 폴리산 무수물이 MN의 재료로 선택되었습니다. 폴리산 무수물은 실온에서 점도가 낮은 액체이기 때문에 MN은 진공 주조와 유사한 가공 방법을 사용하여 홈 가공이 가능합니다. 본 연구에서는 천공 시험을 통해 MN의 모세관력 성능과 MN의 최적 모양 및 크기를 조사했습니다.
Satomitsu IMAI
Nihon University
Kazuki CHIDAISYO
Nihon University
Kosuke YASUDA
Nihon University
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부
Satomitsu IMAI, Kazuki CHIDAISYO, Kosuke YASUDA, "Microneedle of Biodegradable Polyacid Anhydride with a Capillary Open Groove for Reagent Transfer" in IEICE TRANSACTIONS on Electronics,
vol. E106-C, no. 6, pp. 248-252, June 2023, doi: 10.1587/transele.2022OMS0005.
Abstract: Incorporating a tool for administering medication, such as a syringe, is required in microneedles (MNs) for medical use. This renders it easier for non-medical personnel to administer medication. Because it is difficult to fabricate a hollow MN, we fabricated a capillary groove on an MN and its substrate to enable the administration of a higher dosage. MN grooving is difficult to accomplish via the conventional injection molding method used for polylactic acid. Therefore, biodegradable polyacid anhydride was selected as the material for the MN. Because polyacid anhydride is a low-viscosity liquid at room temperature, an MN can be grooved using a processing method similar to vacuum casting. This study investigated the performance of the capillary force of the MN and the optimum shape and size of the MN by a puncture test.
URL: https://global.ieice.org/en_transactions/electronics/10.1587/transele.2022OMS0005/_p
부
@ARTICLE{e106-c_6_248,
author={Satomitsu IMAI, Kazuki CHIDAISYO, Kosuke YASUDA, },
journal={IEICE TRANSACTIONS on Electronics},
title={Microneedle of Biodegradable Polyacid Anhydride with a Capillary Open Groove for Reagent Transfer},
year={2023},
volume={E106-C},
number={6},
pages={248-252},
abstract={Incorporating a tool for administering medication, such as a syringe, is required in microneedles (MNs) for medical use. This renders it easier for non-medical personnel to administer medication. Because it is difficult to fabricate a hollow MN, we fabricated a capillary groove on an MN and its substrate to enable the administration of a higher dosage. MN grooving is difficult to accomplish via the conventional injection molding method used for polylactic acid. Therefore, biodegradable polyacid anhydride was selected as the material for the MN. Because polyacid anhydride is a low-viscosity liquid at room temperature, an MN can be grooved using a processing method similar to vacuum casting. This study investigated the performance of the capillary force of the MN and the optimum shape and size of the MN by a puncture test.},
keywords={},
doi={10.1587/transele.2022OMS0005},
ISSN={1745-1353},
month={June},}
부
TY - JOUR
TI - Microneedle of Biodegradable Polyacid Anhydride with a Capillary Open Groove for Reagent Transfer
T2 - IEICE TRANSACTIONS on Electronics
SP - 248
EP - 252
AU - Satomitsu IMAI
AU - Kazuki CHIDAISYO
AU - Kosuke YASUDA
PY - 2023
DO - 10.1587/transele.2022OMS0005
JO - IEICE TRANSACTIONS on Electronics
SN - 1745-1353
VL - E106-C
IS - 6
JA - IEICE TRANSACTIONS on Electronics
Y1 - June 2023
AB - Incorporating a tool for administering medication, such as a syringe, is required in microneedles (MNs) for medical use. This renders it easier for non-medical personnel to administer medication. Because it is difficult to fabricate a hollow MN, we fabricated a capillary groove on an MN and its substrate to enable the administration of a higher dosage. MN grooving is difficult to accomplish via the conventional injection molding method used for polylactic acid. Therefore, biodegradable polyacid anhydride was selected as the material for the MN. Because polyacid anhydride is a low-viscosity liquid at room temperature, an MN can be grooved using a processing method similar to vacuum casting. This study investigated the performance of the capillary force of the MN and the optimum shape and size of the MN by a puncture test.
ER -